CANINE COMPARATIVE ONCOLOGY & GENOMICS CONSORTIUM

Osteosarcoma

Osteosarcoma is the most common bone tumor of dogs, affecting upwards of 10,000 animals every year. The appendicular skeleton (fore and rear legs) is the most common site, and the disease rapidly spreads to the lungs, as well as other soft tissue sites and bones. A diagnosis of osteosarcoma is made based on typical radiographic (x-ray) findings of the affected bone, and either fine needle aspirate or biopsy of the abnormal tissue. Treatment with surgery (typically amputation) alone is associated with rapid onset of lung metastases and a survival of 4 to 6 months. With surgery (most often amputation) and chemotherapy, survival is extended to 10-12 month post-diagnosis. While approximately 12,000 dogs are diagnosed with osteosarcoma every year, it is far less common in people. Unfortunately, the disease in people is as aggressive as in dogs and treatment with chemotherapy, while helpful in prolonging survival, can have devastating side effects. The CCOGC is interested in this tumor not only because it is uniformly fatal in affected dogs, but because studies by Khanna et al have shown that there is strong similarity between canine and human osteosarcoma based on global gene expression. It is our hope that studies through the CCOGC will help dogs and people with osteosarcoma.

To enjoy being to the fullest it is significant to be sound. How can medications help up? But, there are online pharmacy where you can order medicines without a hitch. There are sundry others. Matters like “when will generic viagra be available” or “viagra stories” are very pops now. You may have heard about “is there a generic viagra“. Variant drugstores describe it as “buy generic viagra“. After all, there is a wide range of explanations and doctors are commonly able to pinpoint your problem through psychological tests. Any drug may affect the way other remedies work, and other medicaments may affect the way it’s works, causing undesirable side effects. The physician have to determine which dosage is most appropriate. In cases of overdose, basic supportive measures should be adopted as required.

Comments are closed.