In 2007 sample collection began at three veterinary institutions, with a focus on collecting three histologies of interest in the field of comparative oncology (osteosarcoma, lymphoma, melanoma). In 2008, four additional collection sites were added plus four additional histologies. In accordance with the initial goals of the CCOGC, the prospective collection of tissues is now available. By making use of the existing CCOCG Biorepository infrastructure, investigators can have biospecimens collected to their specifications for unique research needs.
Standard operating procedures for tissue/sample collection have been established to maximize consistency and are subject to annual review. Informed owner consent and IACUC approval has been obtained prior to collection and samples are de-identified at the collecting site. The biospecimen repository has SOPs in place for the following sample types: tumor tissue, normal tissues, serum, plasma, peripheral blood mononuclear cell preparations, genomic DNA, RNA and urine samples. The repository follows many aspects of the organization and structure of the proposed National Biospecimen Network Blueprint1. A sample shipping and collection database (Tissue Tracker) is used for real time connection between CCOGC collection sites and the central physical bank housed in Frederick, MD. Patient clinical information is contemporarily collected and logged as part of the biorepository effort. Collection protocols and SOPs can be modified for prospective collection.
The prospective collection process proceeds as follows:
- Brief on line application
- Follow up contact by CCOGC to refine your request
- Assessment of network availability, budget, SOP finalization
- Contract process
- Collection begins
From September 1st 2011 you may click here to be directed to a secure site for prospective collection proposals.